TABLE 2.
Detection of M. tuberculosis in 84 CSF samples by Gen-Probe MTD
| Laboratory or clinical diagnosis | Total no. of samples evaluated | No. of samples positive by Gen-Probe MTD |
|---|---|---|
| Infectious agent detected in CSF by culture or immunologic techniques | ||
| Haemophilus influenzae | 16 | 0 |
| Mycobacterium tuberculosis | 5 | 4 |
| Streptococcus pneumoniae | 8 | 0 |
| Pseudomonas aeruginosa | 5 | 0 |
| Neisseria meningitidis | 2 | 0 |
| Escherichia coli | 3 | 0 |
| Staphylococcus aureus | 3 | 0 |
| Streptococcus agalactiae | 2 | 0 |
| Salmonella spp. | 1 | 0 |
| Serratia marcescens | 1 | 0 |
| Treponema pallidum | 1 | 0 |
| No infectious agent identified in CSF but meningitis part of systemic infection | ||
| Clostridium tetani | 2 | 0 |
| Varicella-zoster virus | 4 | 0 |
| Mumps virus | 1 | 0 |
| Human immunodeficiency virus | 1 | 0 |
| Other | ||
| Samples from patients with negative bacterial cultures but who were treated with antimicrobial agents for presumed bacterial meningitis | 8 | 0 |
| Samples from patients with negative bacterial cultures but probable TBM on the basis of clinical criteriaa | 19 | 4 |
| Noninfectious causes of meningitis, central nervous system tumors | 2 | 0 |
| Total | 84 | 8 |
a
Refer to Materials and Methods section for definition of probable TBM.