TABLE 3.
Gen-Probe MTD compared with mycobacterial culture and clinical assessment of patients
| RLU cutoff and Gen-Probe MTD result | No. of patients from whose CSF M. tuberculosis was cultured or with a clinical diagnosis of probable TBMa
|
Sensitivity (%) | Specificity (%) | Positive predictive value (%) | Negative preductive value (%) | |
|---|---|---|---|---|---|---|
| Positive | Negative | |||||
| Cutoff, ≥30,000 RLUs | ||||||
| Positive | 8 | 0 | 33 | 100 | 100 | 79 |
| Negative | 16 | 60 | ||||
| Cutoff, ≥11,000 RLUs | ||||||
| Positive | 20 | 0 | 83 | 100 | 100 | 94 |
| Negative | 4 | 60 | ||||
a
Refer to Materials and Methods section for definition of probable TBM.