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The expression of MDM2 and p53 after I/R-induced AKI and H/R exposure. mRNA levels of (A) p53 and (B) MDM2 detected by qRT-PCR; protein levels C–G Level of p53, MDM2 tested by western blot analysis; H–I Immunohistochemistry was used to detect the expression of p53, MDM2 in (I) control, (II) sham, (III) AKI, (IV) Hexarelin-AKI, and (V) Saline-AKI groups. *P < 0.05, **P < 0.01 versus control; #P < 0.05, ##P < 0.01 versus AKI
