Table 4.
Primary outcomes of allylestrenol versus dydrogesterone stratified by the number of embryo transferred
| Embryo(s) Transferred | Variables | Dydrogesterone (N = 989) | Allylestrenol (N = 989) | P-value |
|---|---|---|---|---|
| 1 | Number of participants | 257 | 372 | |
| ART outcome (%) | ||||
| Clinical pregnancy | 124 (48.2) | 205 (55.1) | 0.107 | |
| Non-pregnancy | 106 (41.2) | 148 (39.8) | 0.776 | |
| Biochemical pregnancy | 27 (10.5) | 19 (5.1) | 0.016* | |
| Clinical pregnancy outcomes (%) | ||||
| Live birth | 99 (38.52) | 171 (45.97) | 0.076 | |
| Abortion | 8 (3.11) | 10 (2.69) | 0.810 | |
| Embryonic demise | 15 (5.84) | 21 (5.65) | 1.000 | |
| Labor induction | 2 (0.78) | 3 (0.81) | 1.000 | |
| Multiple gestations (%) | 2 (1.6) | 1 (0.5) | 0.658 | |
| Number of implantations | 0.059 | |||
| 0 | 131 (51.0) | 166 (44.6) | ||
| 1 | 124 (48.2) | 206 (55.4) | ||
| 2 | 2 (0.8) | 0 (0.0) | ||
| 3 | 0(0.0) | 0(0.0) | ||
| 2 | Number of participants | 680 | 602 | |
| ART outcome (%) | ||||
| Clinical pregnancy | 381 (56.0) | 320 (53.2) | 0.329 | |
| Non-pregnancy | 216 (31.8) | 241 (40.0) | 0.002* | |
| Biochemical pregnancy | 83 (12.2) | 41 (6.8) | 0.002* | |
| Clinical pregnancy outcomes (%) | ||||
| Live birth | 308 (45.29) | 242 (40.20) | 0.075 | |
| Abortion | 22 (3.24) | 26 (4.32) | 0.382 | |
| Embryonic demise | 39 (5.74) | 37 (6.15) | 0.847 | |
| Labor induction | 12 (1.76) | 15 (2.49) | 0.479 | |
| Multiple gestations (%) | 104 (27.3) | 67 (20.9) | 0.062 | |
| Number of implantations | 0.170 | |||
| 0 | 296 (43.5) | 275 (45.7) | ||
| 1 | 246 (36.2) | 227 (37.7) | ||
| 2 | 135 (19.9) | 100 (16.6) | ||
| 3 | 3 (0.4) | 0 (0.0) | ||
| 3 | Number of participants | 52 | 11 | |
| ART Outcome (%) | ||||
| Clinical pregnancy | 21 (40.4) | 3 (27.3) | 0.637 | |
| Non-pregnancy | 24 (46.2) | 5 (45.5) | 1.000 | |
| Biochemical pregnancy | 7 (13.5) | 3 (27.3) | 0.494 | |
| Clinical Pregnancy Outcomes (%) | ||||
| Live birth | 15 (28.85) | 2 (18.18) | 0.712 | |
| Abortion | 4 (7.69) | 0 (0.0) | 1.000 | |
| Embryonic demise | 1 (1.92) | 1 (9.09) | 0.321 | |
| Labor induction | 1 (1.92) | 0 (0.0) | 1.000 | |
| Multiple gestations (%) | 5 (23.8) | 1 (33.3) | 1.000 | |
| Number of implantations | 0.698 | |||
| 0 | 31 (59.6) | 8 (72.7) | ||
| 1 | 12 (23.1) | 2 (18.2) | ||
| 2 | 4 (7.7) | 1 (9.1) | ||
| 3 | 5 (9.6) | 0 (0.0) |
ART assisted reproductive techniques
*P < 0.05