Fig. 1.

Gene set enrichment analysis showing the module activity for patient and control groups in the (A) PTSD, (B) PD and (C) schizophrenia (SCZ) cohorts. A Module 2 genes (n = 158) were found to have significantly increased expression in patients compared to controls in the PTSD cohort. B Genes in modules 1 (n = 222), 5 (n = 61), and 6 (n = 60) were found to be significantly increased in PD patients compared to controls, whereas those in modules 3 (n = 122) and 8 (n = 39) were significantly under-expressed in PD patients compared to controls. C Genes in modules 1 and 6 were found to be significantly increased in schizophrenia patients compared to schizophrenia controls, whereas those in modules 2, 4 and 7 were significantly under-expressed in schizophrenia patients compared to controls. M, module; SCZ, schizophrenia