TABLE 3.
Research progress of exosomes combined with hydrogels in different diseases.
| Hydrogels | Exosomes | Application direction | References |
|---|---|---|---|
| HA-based hydrogel with MnO2/FGF-2 | M2-Exos overexpressing miR-223 | Diabetic Wound Healing | Xiong et al. (2022) |
| GelMA/PEGDA | HUVECs-derived exosomes | Diabetic Wound Healing | Yuan et al. (2022b) |
| Polypeptide-based FHE hydrogel | ADMSCs-Exos | Diabetic Wound Healing | Wang et al. (2019) |
| Pluronic F127 Hydrogel | hUC-MSC-Exos | Diabetic Wound Healing | (Yang et al., 2020) |
| MMP-PEG smart hydrogel | ADSC-Exos | Diabetic Wound Healing | Jiang et al. (2022) |
| PEG hydrogels | M2-Exos | Cutaneous Wound Healing | Kwak et al. (2022) |
| GelMA hydrogel | MSC-Exos | Spinal Cord Repair | Han et al. (2022) |
| GMPE hydrogel | BMSC-Exos | Spinal Cord Repair | Fan et al. (2022) |
| Peptide-modified adhesive hydrogel | Hypoxia-stimulated MSCs-Exos | Spinal Cord Injury | Mu et al. (2022) |
| Hyaluronan-collagen hydrogel | BMSC-Exos | Traumatic Brain Injury | Liu et al. (2023b) |
| Hydrogel based on QCS and OST | MSC-Exos | Disc Degeneration | Guan et al. (2023) |
| ECM hydrogel | ADSC-Exos | Intervertebral Disc Degeneration | Xing et al. (2021) |
| HA hydrogel with SDF-1α | M2-Exos | Bone Regeneration | Chen et al. (2023b) |
| AD/CS/RSF hydrogel | BMSC-Exos | Cartilage Defect Regeneration | Zhang et al. (2021a) |
| HG hydrogel | ADSC-Exos | Cavernous Nerve Injury | Liu et al. (2023a) |