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. 2023 Aug 31;14:1239422. doi: 10.3389/fneur.2023.1239422

Table 5.

Correlations between ATVA subgroups in definite MD patients (n = 114).

Data available, n MD-120 (n = 69) MD-intermediate (n = 29) MD-140 (n = 16) P
Female: male ratio 114 44:25 15:14 5:11 0.053
Unilateral: bilateral MD ratio 114 63:6 29:0 11:5 0.0045
Mean age at MRI, y 114 54.7 ± 13.2 59.2 ± 13.1 61.4 ± 10.5 0.144
Tinnitus, n (%) 83 39 (83.0) 24 (96.0) 10 (90.9) 0.121
Aural fullness, n (%) 64 33 (89.2) 17 (89.5) 8 (100) 1.000
Headache, n (%) 77 20 (44.4) 14 (58.3) 4 (50.0) 0.526
Hearing loss
Mean age of onset, y 44 48.7 ± 14.6 56.8 ± 14.3 50.5 ± 18.8 0.495
Median disease duration, y 44 4.5 (0.0; 17.0) 5.7 (1.6; 12.9) 8.5 (0.3; 29.0) 0.522
Median low Fletcher, dB 97 48. (2; 108) 53 (13; 75) 45 (23; 120) 0.900
Median high Fletcher, dB 97 49 (5; 108) 52 (18; 75) 50 (28; 120) 0.977
Vertigo
Mean age of onset, y 80 48.9 ± 14.2 50.8 ± 12.9 45.4 ± 11.6 0.483
Median disease duration, y 80 2.8 (0.1; 30.7) 4.9 (1.1; 11.0) 16.0 (0.4; 29.0) 0.006
Mean vertigo attack frequency, nr per month 70 6.3 ± 6.9 8.2 ± 10.8 5.0 ± 8.8 0.486
Drop attacks, n (%) 49 2 (6.3) 1 (11.1) 1 (12.5) 0.432
ENG hypofunction, n (%) 39 15 (55.5) 3 (42.9) 2 (40.0) 0.694
EH
Cochlear EH grade 114 1 (0; 2) 1 (0; 2) 1 (0; 2) 0.409
Vestibular EH grade 114 2 (0; 3) 2 (0; 3) 2 (1; 3) 0.589
Perilymph enhancement
Median SIR 114 1.45 (0.68; 5.0) 1.64 (0.71; 5.52) 1.48 (0.93; 3.66) 0.742

EH, endolymphatic hydrops; ENG, electronystagmography; MRI, magnetic resonance imaging; SIR, signal intensity ratio.