Table 5.
Correlations between ATVA subgroups in definite MD patients (n = 114).
| Data available, n | MD-120 (n = 69) | MD-intermediate (n = 29) | MD-140 (n = 16) | P | |
|---|---|---|---|---|---|
| Female: male ratio | 114 | 44:25 | 15:14 | 5:11 | 0.053 |
| Unilateral: bilateral MD ratio | 114 | 63:6 | 29:0 | 11:5 | 0.0045 |
| Mean age at MRI, y | 114 | 54.7 ± 13.2 | 59.2 ± 13.1 | 61.4 ± 10.5 | 0.144 |
| Tinnitus, n (%) | 83 | 39 (83.0) | 24 (96.0) | 10 (90.9) | 0.121 |
| Aural fullness, n (%) | 64 | 33 (89.2) | 17 (89.5) | 8 (100) | 1.000 |
| Headache, n (%) | 77 | 20 (44.4) | 14 (58.3) | 4 (50.0) | 0.526 |
| Hearing loss | |||||
| Mean age of onset, y | 44 | 48.7 ± 14.6 | 56.8 ± 14.3 | 50.5 ± 18.8 | 0.495 |
| Median disease duration, y | 44 | 4.5 (0.0; 17.0) | 5.7 (1.6; 12.9) | 8.5 (0.3; 29.0) | 0.522 |
| Median low Fletcher, dB | 97 | 48. (2; 108) | 53 (13; 75) | 45 (23; 120) | 0.900 |
| Median high Fletcher, dB | 97 | 49 (5; 108) | 52 (18; 75) | 50 (28; 120) | 0.977 |
| Vertigo | |||||
| Mean age of onset, y | 80 | 48.9 ± 14.2 | 50.8 ± 12.9 | 45.4 ± 11.6 | 0.483 |
| Median disease duration, y | 80 | 2.8 (0.1; 30.7) | 4.9 (1.1; 11.0) | 16.0 (0.4; 29.0) | 0.006 |
| Mean vertigo attack frequency, nr per month | 70 | 6.3 ± 6.9 | 8.2 ± 10.8 | 5.0 ± 8.8 | 0.486 |
| Drop attacks, n (%) | 49 | 2 (6.3) | 1 (11.1) | 1 (12.5) | 0.432 |
| ENG hypofunction, n (%) | 39 | 15 (55.5) | 3 (42.9) | 2 (40.0) | 0.694 |
| EH | |||||
| Cochlear EH grade | 114 | 1 (0; 2) | 1 (0; 2) | 1 (0; 2) | 0.409 |
| Vestibular EH grade | 114 | 2 (0; 3) | 2 (0; 3) | 2 (1; 3) | 0.589 |
| Perilymph enhancement | |||||
| Median SIR | 114 | 1.45 (0.68; 5.0) | 1.64 (0.71; 5.52) | 1.48 (0.93; 3.66) | 0.742 |
EH, endolymphatic hydrops; ENG, electronystagmography; MRI, magnetic resonance imaging; SIR, signal intensity ratio.