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. Author manuscript; available in PMC: 2024 Jan 1.
Published in final edited form as: Epilepsia. 2022 Nov 29;64(1):231–246. doi: 10.1111/epi.17462

Figure 6: HFOs in the AD mouse models closely resemble HFOs in 2 animal models of epilepsy.

Figure 6:

(A) Representative example of an HFO (red arrow) recorded from the hippocampus of a mouse where kainic acid was injected. Top trace is wideband recording (0.1–500Hz). The center is filtered trace (250–500Hz), and bottom shows spectral properties of the HFO in the 250–600Hz time-frequency domain.

(B) Same as in A but for an HFO recorded from the hippocampus of a PILO-treated mouse.

(C) Comparison of HFO duration between AD, IHKA and PILO models. One-way ANOVA found no significant differences in HFO duration between models (F(2, 23)=1.84, p=0.18).

(D) Same as in C but for spectral frequency. As in the case of HFO duration, one-way ANOVA found no significant differences between models (F(2, 23)=1.66, p=0.21).