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. 2023 Aug 31;14:1239507. doi: 10.3389/fphar.2023.1239507

TABLE 2.

The overarching table which includes the themes identified from the synthesis and their compositions.

Reasons why people purchase prescription medicines on the internet. (sources)
• Perceived benefits: Positive consequences and outcomes that consumers expect to receive from purchasing prescription medicines on the Internet.
⁃ Convenience purchase: Save effort, avoid long waiting times, helpful when the patient is in a bed rest period, fast deliveries, and 24/7 accessibility. (2QL, 3QL, 4QL, 1QN, 5QN, 6QN, 7QN, 8QN, 1MX)
⁃ Privacy. (2QL, 4QL, 1QN, 7QN, 11QN)
⁃ Lower cost. (2QL, 3QL, 4QL, 1QN, 3QN, 4QN, 5QN, 6QN, 8QN, 9QN, 10QN, 11QN, 12MX)
⁃ Bypassing gatekeepers: Bypass doctors who refuse to prescribe prescription medicines. (11QN)
⁃ Medicines availability
- Availability of extra quantities. (3QN)
- Availability of medicines that are not available locally. (1QN, 4QN, 5QN, 6QN, 8QN, 1MX)
- Being able to purchase unlicensed medicines. (3QN, 8QN)
- Wide products choices. (1QN, 4QN, 8QN)
- Brand medicines availability. (3QN, 1MX)
⁃ Better product quality. (1QN, 4QN, 5QN, 6QN, 8QN, 9QN)
⁃ Avoid withdrawal symptoms for patients using controlled medicines. (11QN)
Perceived risks: Negative outcomes associated with purchasing prescription medicines using the Internet.
⁃ Health risks
- Possibility of purchasing fake medicines. (4QL, 5QN, 1MX)
- Absence of medical oversight complications, for example, the possibility of misusing medicines. (2QL, 3QN, 5QN, 9QN)
⁃ Financial risks. (4QL)
⁃ Inferior product quality. (2QL, 4QN, 5QN, 7QN, 9QN, 1MX)
⁃ Engaging in illegal behaviour (buying from Unlicensed websites or buying unlicensed medicines). (4QN, 7QN)
⁃ No privacy and confidentiality. (7QN)
⁃ Delayed deliveries. (5QN)
Emotions: A complex reactions, feelings, and affective states that motivate consumers to purchase prescription medicines from the internet
⁃ Desperation caused by medication unavailability. (4QL)
⁃ Fear of the purchase risks. (2QL)
⁃ Hate going to the doctor. (11QN)
Facilitators: Factors that increase consumers’ ability to control the behaviour of purchasing prescription medicines using the web, thus, facilitating the purchase
⁃ Facilitators offered by the online sellers of medicines that make it easier for customers to purchase their product
- Websites usability. (2QL)
- Easy accessibility as prescription medicines without requiring a prescription. (4QL, 1QN, 3QN, 4QN, 6QN, 8QN, 9QN)
- Fast shipping option. (7QN)
- Refill reminders by email. (7QN)
- Products can be compared faster. (5QN)
- Product information and providing instruction on how to use prescription medicines. (1QN, 5N, 7QN, 8QN, 10QN)
- Online sellers marketing such as promotion and discounts which make the purchase affordable to consumers. (1QL, 2QL, 10QN, 12QN, 1MX)
⁃ Facilitators offered by social media
- Easy and private communication. (1QL, 3QN)
- Act as a source of medical information offered by the support groups available on the different social media platforms. (1QL, 2QL)
Barriers: Factors that decrease consumers’ ability to control the behaviour of purchasing prescription medicines using the web, thus, impeding the purchase
⁃ Website-specific barriers (barriers that delay the purchase until consumers can find an alternative)
- Absent of suitable payment option. (4QL)
- Payment method security. (2QL)
- Website language and instructions are in an unknown foreign language. (3QN)
⁃ General barriers (barriers that prevent the purchase)
- Financial capabilities. (4QL)
- Consumers do not know how to use the medicine. (3QN, 5QN)
Knowledge: Consumer’s knowledge about the purchase (procedural knowledge and the knowledge about the risks of the purchase)
⁃ Computer and internet literacy. (2QL)
⁃ Knowledge about the risks of the purchase. (2QL, 3QL, 3QN, 10QN, 12QN)
⁃ The difficulty in distinguishing between legal and illegal online pharmacies. (3QL, 3QN)
Trusting beliefs: Factors that lead consumers to trust the online sellers of medicines
⁃ Past purchase experience (either positive or negative experience). (3QN, 6QN, 7QN, 12QN, 1MX)
⁃ Customer review (either positive or negative review and feedback). (2QL, 4QL, 6QN, 12QN, 1MX)
⁃ Availability of secure payment option. (2QL)
⁃ Clear information about the product and vendors. (6QN, 7QN)
Social influencing factors: Social factors that could encourage or discourage consumers’ decision to purchase prescription medicines using the Internet.
⁃ Family and friends. (2QL, 3QN, 6QN, 12QN, 1MX)
⁃ Peer influence: People who are in the same situation. (2QL)
⁃ Healthcare provider: Doctors or pharmacists. (2QL, 3QN, 1MX)
⁃ People at online support groups. (2QL)
Environmental factors: Any external environmental condition that encourages or discourages the purchase
⁃ Barriers to accessing the clinic (logistical difficulties, financial difficulties). (4QL)
⁃ Restricted options (few alternatives are available in local market sectors). (1MX)
⁃ Sellers’ marketing (advertising and pop-up ads). (2QL)
⁃ Medicines shortages. (8QN)
⁃ Unsatisfied with the quality of clinical services provided in clinics or local community pharmacies. (1QN, 1MX)
⁃ The Coronavirus pandemic (COVID-19). (2QN)
Consumer attributes: Demographic, socioeconomics, health information, and the internet using habits and characteristics that could affect the purchasing decision
⁃ Age. (1QN, 2 QN, 4 QN, 5QN, 6QN, 7QN, 11QN, 1 MX)
⁃ Sex. (1QN, 2QN, QN, 7QN)
⁃ Marital status. (2QN)
⁃ Income level. (1QN, 7QN)
⁃ Educational level. (1QN, 2QN, 3QN, 4QN, 5QN, 7QN, 1MX)
⁃ Employment. (1QN, 3QN)
⁃ Health insurance availability. (11QN)
⁃ Time spent on the internet. (5QN, 10QN)
⁃ Social media affinity. (3QN)
⁃ Internet purchase frequency in general. (5QN)