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. 2023 Jun 1;13(9):3782–3801. doi: 10.1016/j.apsb.2023.05.034

Figure 7.

Figure 7

The anti-inflammatory effect of SMU-Y6 in mice colitis induced by DSS. (A) Body weight of mice of each group. (B) Photograph of mice colon on Day 8. (C) TNF-α and IL-6 were measured in serum and local colonic tissue after mice treated with vehicle, 5 mg/kg SMU-Y6, 25 mg/kg SMU-Y6 and 25 mg/kg dexamethasone. (D) HE staining results and immunohistochemical analysis of iNOs (E) and MPO (F) in colon tissue. Results of mice were treated with vehicle, 5 mg/kg SMU-Y6, 25 mg/kg SMU-Y6 and 25 mg/kg dexamethasome. (G) Flow cytometry analysis of neutrophile in local colon tissue.