TABLE 1.

QC-PCR and clinical data^a

Patient no.	Sex	Age (yr)	No. of HSV-1 DNA copies/μl	Time of disease (days)	Time of acyclovir (days)	Glasgow score	Detection of lesion by CT	Impairment after 3 mo
1	F	48	1.8 × 104	7	2	14	Yes	Moderate
2	M	61	1.2 × 104	6	2	13	Yes	Mild
3	F	48	8.0 × 103	12	0	5	Yes	Severe
4	M	48	7.9 × 103	6	3	13	Yes	Mild
5	M	15	7.9 × 103	4	1	13	Yes	Moderate
6	F	59	3.1 × 103	11	0	13	Yes	Moderate
7	M	59	2.3 × 103	5	2	14	Yes	Moderate
8	F	59	1.9 × 103	5	1	6	Yes	Death
9	M	12	1.5 × 103	3	0	7	Yes	Mild
10	F	41	3.2 × 101	2	1	15	No	Normal
11	F	4	3.1 × 101	6	0	12	No	Normal
12	F	47	<2.5 × 101	4	3	15	Yes	Normal
13	M	17	<2.5 × 101	3	1	11	No	Normal
14	F	1.5	<2.5 × 101	1	0	15	No	Moderate
15	F	44	<2.5 × 101	10	4	15	No	Normal
16	M	22	<2.5 × 101	1	0	14	No	Normal

^aTime of disease and time of acyclovir refer to the duration of disease and duration of therapy, respectively, at the time that the CSF was obtained. Glasgow scores refer to the level of consciousness at the time of enrollment. Patients were categorized as follows: 15, alert; 12 to 14, lethargic; 7 to 11, semicomatose; <7, comatose. F, female; M, male.