Table 3.
Bi-variable and multi-variable Cox regression analyses for predicting mortality in children with diabetic ketoacidosis in the Comprehensive Specialized Referral Hospitals of West Amhara Region, Northwest Ethiopia, 2022 (N=401).
| Variables | Category | Survival status | CHR (95% CI) | AHR (95% CI) | P-value | |
|---|---|---|---|---|---|---|
| Event | Censored | |||||
| Age | <5 | 19 | 72 | 0.77 (0.58, 1.02) | 4.38 (1.41, 13.7) | 0.011* |
| 5-10 | 15 | 137 | 0.93 (0.74,1.17) | 3.06 (1.06, 8.8) | 0.038* | |
| 11-14 | 6 | 152 | 1 | 1 | ||
| Gender | Male | 10 | 176 | 1 | 1 | |
| Female | 30 | 185 | 0.79 (0.65, 0.98) | 2.5 (1.14, 5.79) | 0.023* | |
| Residence | Urban | 5 | 144 | 1 | 1 | |
| Rural | 35 | 217 | 0.79 (0.64, 0.97) | 2.86 (1.01,8.11) | 0.049* | |
| Child’s education status | Not started | 16 | 49 | 0.71 (0.52, 0.96) | 2.01 (0.76,5.35) | 0.162 |
| KG | 10 | 76 | 0.84 (0.65, 1.09) | 0.95 (0.38,2.38) | 0.906 | |
| Primary | 14 | 236 | 1 | 1 | ||
| Infection | Yes | 35 | 213 | 0.73 (0.59, 0.90) | 1.2 (0.397,3.59) | 0.753 |
| No | 5 | 148 | 1 | 1 | ||
| Co-morbidity | Yes | 24 | 112 | 0.59 (0.48, 0.75) | 0.96 (0.45,2.05) | 0.914 |
| No | 16 | 249 | 1 | 1 | ||
| Hypoglycemia | Yes | 24 | 47 | 0.49 (0.36, 0.68) | 4.63 (2.13,10.06) | 0.001* |
| No | 16 | 314 | 1 | 1 | ||
| Medication adherence | Yes | 12 | 202 | 1.52 (1.21, 1.82) | 0.74 (0.32,1.71) | 0.481 |
| No | 28 | 159 | 1 | 1 | ||
| Recurrent DKA diagnosed | One time | 9 | 145 | 1 | 1 | |
| Two times | 10 | 75 | 0.99 (0.75, 1.31) | 1.46 (0.55, 3.86) | 0.45 | |
| Three times | 11 | 117 | 0.93 (0.73, 1.18) | 1.3 (0.5, 3.31) | 0.59 | |
| Four or more | 10 | 24 | 0.47 (0.30,0.74) | 0.86 (0.19, 3.85) | 0.85 | |
| Severity of DKA | Mild | 5 | 79 | 1 | 1 | |
| Moderate | 10 | 146 | 0.75 (0.57, 0,99) | 0.56 (0.18, 1.83) | 0.330 | |
| Severe | 25 | 136 | 0.66 (0.51, 0.88) | 1.04 (0.32, 3.49) | 0.953 | |
| Glasgow Coma Scale | Mild | 12 | 207 | 1 | 1 | |
| Moderate | 19 | 139 | 0.96 (0,77, 1.21) | 1.2 (0.45, 2.83) | 0.790 | |
| Severe | 9 | 15 | 0.33 (0.19, 0.57) | 1.06 (0.91, 2.32) | 0.340 | |
| Vomiting | Yes | 33 | 230 | 1.01 (0.81,1.25) | 1.81 (0.65, 5.02) | 0,254 |
| No | 7 | 131 | 1 | 1 | ||
* indicates the significant variables which is P-value less than 0.05.