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. 2023 Aug 31;4:1204133. doi: 10.3389/fcdhc.2023.1204133

Table 3.

Bi-variable and multi-variable Cox regression analyses for predicting mortality in children with diabetic ketoacidosis in the Comprehensive Specialized Referral Hospitals of West Amhara Region, Northwest Ethiopia, 2022 (N=401).

Variables Category Survival status CHR (95% CI) AHR (95% CI) P-value
Event Censored
Age <5 19 72 0.77 (0.58, 1.02) 4.38 (1.41, 13.7) 0.011*
5-10 15 137 0.93 (0.74,1.17) 3.06 (1.06, 8.8) 0.038*
11-14 6 152 1 1
Gender Male 10 176 1 1
Female 30 185 0.79 (0.65, 0.98) 2.5 (1.14, 5.79) 0.023*
Residence Urban 5 144 1 1
Rural 35 217 0.79 (0.64, 0.97) 2.86 (1.01,8.11) 0.049*
Child’s education status Not started 16 49 0.71 (0.52, 0.96) 2.01 (0.76,5.35) 0.162
KG 10 76 0.84 (0.65, 1.09) 0.95 (0.38,2.38) 0.906
Primary 14 236 1 1
Infection Yes 35 213 0.73 (0.59, 0.90) 1.2 (0.397,3.59) 0.753
No 5 148 1 1
Co-morbidity Yes 24 112 0.59 (0.48, 0.75) 0.96 (0.45,2.05) 0.914
No 16 249 1 1
Hypoglycemia Yes 24 47 0.49 (0.36, 0.68) 4.63 (2.13,10.06) 0.001*
No 16 314 1 1
Medication adherence Yes 12 202 1.52 (1.21, 1.82) 0.74 (0.32,1.71) 0.481
No 28 159 1 1
Recurrent DKA diagnosed One time 9 145 1 1
Two times 10 75 0.99 (0.75, 1.31) 1.46 (0.55, 3.86) 0.45
Three times 11 117 0.93 (0.73, 1.18) 1.3 (0.5, 3.31) 0.59
Four or more 10 24 0.47 (0.30,0.74) 0.86 (0.19, 3.85) 0.85
Severity of DKA Mild 5 79 1 1
Moderate 10 146 0.75 (0.57, 0,99) 0.56 (0.18, 1.83) 0.330
Severe 25 136 0.66 (0.51, 0.88) 1.04 (0.32, 3.49) 0.953
Glasgow Coma Scale Mild 12 207 1 1
Moderate 19 139 0.96 (0,77, 1.21) 1.2 (0.45, 2.83) 0.790
Severe 9 15 0.33 (0.19, 0.57) 1.06 (0.91, 2.32) 0.340
Vomiting Yes 33 230 1.01 (0.81,1.25) 1.81 (0.65, 5.02) 0,254
No 7 131 1 1

* indicates the significant variables which is P-value less than 0.05.