Impact of consuming a low-fat diet (LFD) vs. high-fat diet (HFD) on food intake (A), calorie intake (B), body weight changes (C), organ impact (D), systemic hemoglobin (E) and organ weight (F). Female A/J mice were fed LFD or HFD starting at weaning. The average amount of food intake was higher in the LFD mice (Fig. 3A); although the average daily calorie intake was lower in this group (Fig. 3B). Weight gain was higher in mice consuming the HFD (Fig. 3C). There was an increase in the size of the spleen, liver, and kidney in the HFD group (Fig. 3D, F); and a decrease in hemoglobin levels in the HFD group (Fig. 3E).