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. 2023 Sep 1;14:1213734. doi: 10.3389/fphar.2023.1213734

TABLE 6.

Comparison of plasma concentration between twins.

Parameters The first of the twins in Group III (n = 5) The second of the twins in Group III (n = 5) The first of the twins in Group IV (n = 7) The second of the twins in Group IV (n = 7) p-Value
Etomidate
UV, ng/mL 400.23 ± 90.87 345.00 ± 148.39 346.30 ± 138.41 283.85 ± 123.95 0.939
UA, ng/mL 239.16 ± 93.26 164.80 ± 51.04 167.32 ± 46.32 163.69 ± 41.12 0.599
UV/MA ratio 0.78 ± 0.13 0.66 ± 0.23 0.67 ± 0.29 0.53 ± 0.21 0.533
UA/UV ratio 0.60 ± 0.18 0.54 ± 0.26 0.55 ± 0.28 0.65 ± 0.26 0.897
Remifentanil
UV, ng/mL 1.74 ± 1.06 1.47 ± 0.88 1.60 ± 0.50 1.53 ± 0.39 0.496
UA, ng/mL 1.00 ± 1.08 0.82 ± 1.05 0.51 ± 0.41 0.48 ± 0.44 0.131
UV/MA ratio 0.42 ± 0.18 0.37 ± 0.17 0.52 ± 0.23 0.50 ± 0.21 0.338
UA/UV ratio 0.47 ± 0.29 0.45 ± 0.41 0.37 ± 0.29 0.35 ± 0.33 0.867
Rocuronium bromide
UV, ng/mL 1.13 ± 0.78 0.83 ± 0.68 0.73 ± 0.56 0.60 ± 0.29 0.482
UA, ng/mL 058 ± 0.36 0.43 ± 0.36 0.35 ± 0.23 0.34 ± 0.13 0.453
UV/MA ratio 0.20 ± 0.10 0.14 ± 0.09 0.16 ± 0.18 0.10 ± 0.06 0.550
UA/UV ratio 0.54 ± 0.14 0.52 ± 0.06 0.55 ± 0.17 0.60 ± 0.18 0.774

MA, maternal arterial, UA, umbilical arterial, UV, umbilical venous.