Table 1.
Demographic summary in control subjects and patients with schizophrenia.
| Control | Schizophrenia | p valuea | |
|---|---|---|---|
| N | 117 | 218 | |
| Age | 39.8 ± 11.3 | 45.9 ± 11.5 | <.0001*** |
| Sex (male/female) | 41/76 | 116/102 | 0.0014** |
| HbA1c (%) | 5.4 ± 0.3 | 5.4 ± 0.4 | 0.912 |
| eGFR (ml/min/1.73m2) | 88.6 ± 14.4 | 85.5 ± 14.3 | 0.063 |
| PEN (ng/ml) | 36.2 ± 8.7 | 77.6 ± 102.1 | <.0001*** |
| GlcA (Z-score)b | −0.325 ± 0.626 | 0.174 ± 1.12 | <.0001*** |
Abbreviations: PEN, pentosidine; GlcA, glucuronic acid; HbA1c, hemoglobin A1c; eGFR, estimated glomerular filtration rate.
a
Statistical differences were determined using the Mann–Whitney test. Differences were considered statistically significant at P < 0.05.
b
GlcA values were normalized by z-score.