Table 4.
Molecular-grade prediction performance | ||
---|---|---|
Train | Validation | |
Percentage of PPV (for high-grade) | 94 (80–99) | 88 (62–98) |
PPV [%] (for high-grade) and Specificity [%] | 94 (79–99) | 95 (83–99) |
Odds ratio | 17.8 (3.9–81.4) | 15.2 (3.1–74.5) |
Total samples (HG/LG) | 91 (59/32) | 70 (31/39) |
Note: Percentage of PPV is UroAmp-predicted HG that is confirmed by HG pathology. Specificity is the percent of pathologically LG samples not classified as HG by UroAmp. Odds ratio is the fold-increase in odds that a tumor is pathologically HG when predicted UroAmp HG. Values in parenthesis denote 95% confidence intervals.