Table 1.
Top binding amino acids with the strongest affinities toward the NLS peptides
Rank | KKPK | KKPKKE | ||
---|---|---|---|---|
Amino acid | Amino acid | |||
1 | Trp161 | 0.96 0.00 | Trp161 | 0.99 0.00 |
2 | Ser79 | 0.83 0.01 | Ser79 | 0.97 0.00 |
3 | Asn118 | 0.77 0.03 | Asn118 | 0.97 0.00 |
4 | Asp200 | 0.73 0.01 | Gly80 | 0.95 0.00 |
5 | Gly80 | 0.69 0.03 | Ala78 | 0.95 0.00 |
6 | Ala78 | 0.68 0.03 | Asp122 | 0.95 0.00 |
7 | Thr85 | 0.68 0.03 | Thr85 | 0.95 0.00 |
8 | Asp122 | 0.67 0.04 | Trp114 | 0.92 0.00 |
9 | Trp114 | 0.66 0.02 | Thr81 | 0.86 0.00 |
10 | Glu196 | 0.60 0.01 | Trp72 | 0.86 0.00 |
Amino acids in bold belong to minNLS or coreNLS binding sites.