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. 2023 Aug 4;122(17):3476–3488. doi: 10.1016/j.bpj.2023.07.024

Table 1.

Top binding amino acids with the strongest affinities toward the NLS peptides

Rank KKPK KKPKKE
Amino acid Pc(i) Amino acid Pc(i)
1 Trp161 0.96 ± 0.00 Trp161 0.99 ± 0.00
2 Ser79 0.83 ± 0.01 Ser79 0.97 ± 0.00
3 Asn118 0.77 ± 0.03 Asn118 0.97 ± 0.00
4 Asp200 0.73 ± 0.01 Gly80 0.95 ± 0.00
5 Gly80 0.69 ± 0.03 Ala78 0.95 ± 0.00
6 Ala78 0.68 ± 0.03 Asp122 0.95 ± 0.00
7 Thr85 0.68 ± 0.03 Thr85 0.95 ± 0.00
8 Asp122 0.67 ± 0.04 Trp114 0.92 ± 0.00
9 Trp114 0.66 ± 0.02 Thr81 0.86 ± 0.00
10 Glu196 0.60 ± 0.01 Trp72 0.86 ± 0.00

Amino acids in bold belong to minNLS or coreNLS binding sites.