TABLE 3.
The role of circRNAs in AS.
| circRNA | The expression level of circRNA in AS | Function in AS | References |
|---|---|---|---|
| circ_0090231 | Up | Promotes endothelial cell scorching | Ge et al. (2021) |
| circ_0026218 | Down | Reduces endothelial cell apoptosis and inhibits inflammatory response | Yang et al. (2023a) |
| circRNA_06206 | Down | Inhibits angiogenesis | Yuan et al. (2023) |
| circ_0008896 | Up | Promotes endothelial cell apoptosis, angiogenesis and inflammatory response | Liu et al. (2023) |
| circ_0000280 | Down | Inhibits proliferation of smooth muscle cells | Wang et al. (2022b) |
| circ COL1A1 | Up | Promotes the conversion of vascular smooth muscle cells from a contractile to a synthetic phenotype | Ye et al. (2023) |
| circ_0007478 | Up | Promotes foam cell formation | Ye et al. (2022) |
| circ_0007478 | Up | Inhibits endothelial cell viability and promotes endothelial damage | Zhang et al. (2022a) |
| circNMD 3 | Down | Reduces endothelial cell inflammation and oxidative stress | Xiu et al. (2022) |
| circ_0030042 | Up | Promotes the proliferation and migration of vascular smooth muscle cells | Ma et al. (2022) |