Figure 5.

Variant-specific estimates of penetrance by age can now be derived

The plot depicts the age-related cumulative penetrance of five HCM-associated rare variants across age deciles from variant group 2. Presented is the estimated penetrance and 95% confidence interval. The x axis starts in the decade of the 20s as the analysis of these variants was underpowered for teens and younger. “20s” here means “by 30 years old.”