TABLE 2.
Average diagnostic performance of 10-fold cross-validation on different CHAID models for tumor recurrence prediction
| Accuracy (%) | Sensitivity (%) | Specificity (%) | AUC (%) | |
|---|---|---|---|---|
| (I) All | 89.5 (81.1–95.1) | 85.0 (73.4–92.9) | 100 (86.8–100) | 92.5 (84.8–97.1) |
| (IIA) APTw | 86.0 (76.7–89.9) | 70.6 (58.7–75.4) | 96.2 (88.4–99.3) | 87.8 (79.0–93.9) |
| (IIB) T1w | 74.4 (63.9–83.2) | 96.7 (88.5–99.6) | 23.1 (9.0–43.7) | 59.9 (48.7–70.3) |
| (IIC) T2w | 76.7 (66.3–83.6) | 58.3 (45.9–66.6) | 90.0 (81–95.9) | 77.9 (67.6–86.1) |
| (IID) FLAIR | 83.7 (74.2–90.8) | 88.3 (77.4–95.2) | 73.1 (52.2–88.4) | 80.7 (70.8–88.4) |
| (IIE) Gd-T1w | 76.7 (70.3–76.7) | 100 (53.5–100) | 75.0 (71.5–75) | 61.5 (50.4–71.8) |
| (III) T1w, T2w, FLAIR, Gd-T1w | 82.6 (72.9–89.9) | 85.0 (73.4–92.9) | 76.9 (56.4–91) | 81.0 (71.1–88.6) |
| (IV) T1w, T2w, FLAIR, APTw | 90.7 (82.5–95.9) | 88.3 (77.4–95.2) | 96.2 (80.4–99.9) | 92.2 (84.4–96.9) |
Note: Data in parentheses are 95% confidence intervals. Based on the comparison of ROC curves, AUCs between I and III and between III and IV were significantly different (P = 0.031 and 0.006, respectively); AUCs between IIA and IIB and between IIA and IIE were also significantly different (P < 0.0001); AUCs between IIA and IIC were marginally significantly different (P = 0.061).