Table 2.
“SNP - GMV” associations | Effect direction | |||||
---|---|---|---|---|---|---|
Schizophrenia | Effect | Accumbens | Brainstem | Caudate | risk or effect | |
SNP | -risk allele | allele | 28,697 | 28,809 | 30,153 | alleles |
rs2238096 | a | a | >0.05 | 0.017 | 0.040 | ↑↑ |
rs11062298 | A | C | 0.048 | >0.05 | >0.05 | ↑↓ |
rs11062299 | T | C | 0.045 | >0.05 | >0.05 | ↑↓ |
rs10848682 | C | G | 0.042 | >0.05 | >0.05 | ↑↓ |
rs10774052 | C | T | 0.034 | >0.05 | >0.05 | ↑↓ |
rs7315556 | G | A | 0.034 | >0.05 | >0.05 | ↑↓ |
rs2302729 | C | C | 0.028 | 0.018 | >0.05 | ↑↑ |
The italic lowercase risk allele is a major allele (f>0.5). ↑ and ↓, increase or decrease risk for disease or GMV, respectively, referencing to the disease-risk alleles.