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. 2023 Sep 14;22:248. doi: 10.1186/s12933-023-01979-1

Table 2.

Plasma oxysterols levels and inflammation biomarkers in controls and diabetic patients. Data are expressed as medians [25th-75th percentiles]. Groups were compared with a Mann- Whitney non-parametric test

Controls Type 2 diabetics p.overall
Oxysterols (mmol/mol cholesterol)
7α-Hydroxycholesterol 0.31 [0.21;0.42] 0.36 [0.26;0.46] 0.029
7β-Hydroxycholesterol 0.39 [0.26;0.52] 0.47 [0.33;0.66] 0.040
7-ketocholesterol 0.85 [0.59;1.37] 0.90 [0.70;1.38] 0.166
25-hydroxycholesterol 0.14 [0.11;0.19] 0.14 [0.10;0.22] 0.854
27-hydroxycholesterol 0.04 [0.03;0.05] 0.04 [0.03;0.06] 0.652
Hs CRP (mg/L). 1.85 [0.96;4.75] 3.24 [1.17;8.75] 0.028
IL-1β (ng/l) 0.05 [0.05;0.08] 0.06 [0.05;0.12] 0.017
IL-18 (µg/l) 0.61 [0.45;0.85] 0.70 [0.50;0.96] 0.098
IL-6 (ng/l) 5.14 [4.02;10.1] 4.97 [3.73;7.43] 0.273