Table 3.
Lysophosphatidylcholine and oxysterols in carotid plaques from control and type 2 diabetic patients. Data are expressed as mean +/- S.D. (for normal distribution), medians [25th-75th percentiles]. Groups were compared with a Student’s test or Kruskall-Wallis non-parametric test
Controls | Type 2 Diabetics | p.overall | |
---|---|---|---|
N = 98 | N = 101 | ||
Total LPC (mmol/mol cholesterol) |
5.23 [3.05;6.93] | 4.84 [3.36;8.10] | 0.941 |
LPC relative levels | |||
16.0.LPC.sn1 | 40.5 (2.81) | 40.8 (3.10) | 0.543 |
16.0.LPC.sn2 | 6.84 [6.07;7.46] | 6.82 [6.12;7.55] | 0.977 |
18.2.LPC.sn1 | 5.38 [4.08;6.84] | 5.26 [3.89;6.89] | 0.829 |
18.2.LPC.sn2 | 1.06 [0.74;1.37] | 1.02 [0.80;1.44] | 0.946 |
18.1.LPC.sn1 | 10.0 (2.04) | 9.83 (1.81) | 0.505 |
18.1.LPC.sn2 | 1.83 [1.54;2.23] | 1.88 [1.52;2.12] | 0.870 |
18.0.LPC.sn1 | 26.2 (4.18) | 25.5 (4.28) | 0.294 |
18.0.LPC.sn2 | 4.52 [3.92;5.44] | 4.49 [3.65;5.29] | 0.333 |
20.4.LPC.sn1 | 1.50 [1.13;1.98] | 1.55 [1.19;2.26] | 0.132 |
20.4.LPC.sn2 | 0.37 [0.26;0.62] | 0.45 [0.34;0.75] | 0.013 |
20.3.LPC.sn1 | 0.84 [0.65;1.07] | 0.87 [0.68;1.21] | 0.201 |
20.3.LPC.sn2 | 0.20 [0.14;0.26] | 0.19 [0.15;0.30] | 0.337 |
Oxysterols (mmol/mol cholesterol) | |||
27-Hydroxycholesterol | 3.33 [2.02;7.25] | 3.35 [1.84;6.74] | 0.945 |
25-Hydroxycholesterol | 0.39 [0.28;0.62] | 0.43 [0.30;0.75] | 0.273 |
7α-Hydroxycholesterol | 0.75 [0.44;1.11] | 0.78 [0.49;1.47] | 0.246 |
7β-Hydroxycholesterol | 0.94 [0.64;1.27] | 1.11 [0.70;1.76] | 0.063 |
7-ketocholesterol | 2.03 [1.16;3.88] | 1.93 [1.11;3.94] | 0.940 |