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. 2023 Sep 14;22:248. doi: 10.1186/s12933-023-01979-1

Table 3.

Lysophosphatidylcholine and oxysterols in carotid plaques from control and type 2 diabetic patients. Data are expressed as mean +/- S.D. (for normal distribution), medians [25th-75th percentiles]. Groups were compared with a Student’s test or Kruskall-Wallis non-parametric test

Controls Type 2 Diabetics p.overall
N = 98  N = 101

Total LPC

(mmol/mol cholesterol)

5.23 [3.05;6.93] 4.84 [3.36;8.10] 0.941
LPC relative levels
16.0.LPC.sn1 40.5 (2.81) 40.8 (3.10) 0.543
16.0.LPC.sn2 6.84 [6.07;7.46] 6.82 [6.12;7.55] 0.977
18.2.LPC.sn1 5.38 [4.08;6.84] 5.26 [3.89;6.89] 0.829
18.2.LPC.sn2 1.06 [0.74;1.37] 1.02 [0.80;1.44] 0.946
18.1.LPC.sn1 10.0 (2.04) 9.83 (1.81) 0.505
18.1.LPC.sn2 1.83 [1.54;2.23] 1.88 [1.52;2.12] 0.870
18.0.LPC.sn1 26.2 (4.18) 25.5 (4.28) 0.294
18.0.LPC.sn2 4.52 [3.92;5.44] 4.49 [3.65;5.29] 0.333
20.4.LPC.sn1 1.50 [1.13;1.98] 1.55 [1.19;2.26] 0.132
20.4.LPC.sn2 0.37 [0.26;0.62] 0.45 [0.34;0.75] 0.013
20.3.LPC.sn1 0.84 [0.65;1.07] 0.87 [0.68;1.21] 0.201
20.3.LPC.sn2 0.20 [0.14;0.26] 0.19 [0.15;0.30] 0.337
Oxysterols (mmol/mol cholesterol)
27-Hydroxycholesterol 3.33 [2.02;7.25] 3.35 [1.84;6.74] 0.945
25-Hydroxycholesterol 0.39 [0.28;0.62] 0.43 [0.30;0.75] 0.273
7α-Hydroxycholesterol 0.75 [0.44;1.11] 0.78 [0.49;1.47] 0.246
7β-Hydroxycholesterol 0.94 [0.64;1.27] 1.11 [0.70;1.76] 0.063
7-ketocholesterol 2.03 [1.16;3.88] 1.93 [1.11;3.94] 0.940