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. 2023 Sep 15;17:85. doi: 10.1186/s40246-023-00532-1

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — Summary of the common findings between the analysis of RTT-MECP2 patients versus healthy controls and RTT-like patients versus healthy controls. A Common 63 DEGs (25 upregulated and 38 downregulated), coloured by Biological Process (BP). B Gene set enrichment analysis results for the shared 63 DEGs coloured by BP. C Common 81 DEPs (39 upregulated and 42 downregulated), coloured by BP. D Gene set enrichment analysis results for the shared 81 DEGs coloured by BP