Table 1.

Composition of the studied cohort, which consists of individuals with Rett syndrome (RTT) with mutations in MECP2, MECP2 duplication syndrome (MDS) and Rett-like (RTT-like) with mutations in different genes that are not MECP2 and healthy controls. ‘Age’ and ‘Duration of disease’ are given in years; Mean ± Standard Deviation with available data (Additional file 5: Table S2)

Individuals	Age	Duration of disease	Female	Male	Total
RTT	9 ± 6	12 ± 2	21	1	22
MDS	7 ± 6	6 ± 6	–	15	15
RTT-like	12 ± 7	11 ± 7	8	4	12
CDKL5	9.5 ± 10	9 ± 10.5	1	3	4
FOXG1	9.5 ± 3.5	9 ± 3.5	1	1	2
NR2F1	9	8.7	1	–	1
GRIN2B	9	8.7	1	–	1
AHDC1	13	11	1	–	1
Unknown mutation	18 ± 5	17 ± 5	3	–	3
Healthy controls	18 ± 14	–	7	6	13