Table 2.
Genes with concordant differential expression in transcriptomics and proteomics that are involved in the main biological processes identified via enrichment analysis
| Gene | Direction | Biological process | Potential TF |
|---|---|---|---|
| AFAP1 | Upregulated | Cytoskeletal processes | SRF |
| FMNL2 | Upregulated | Cytoskeletal processes | CREB1 |
| FNBP1L | Upregulated | Cytoskeletal processes | CREB1 |
| KIF3A | Upregulated | Cytoskeletal processes | – |
| MARCKSL1 | Upregulated | Cytoskeletal processes | – |
| PLS3 | Upregulated | Cytoskeletal processes | SRF |
| ARMC9 | Downregulated | Cytoskeletal processes | SRF |
| ARHGEF1 | Downregulated | Cytoskeletal processes | – |
| CDC42EP1 | Downregulated | Cytoskeletal processes | – |
| IQGAP3 | Downregulated | Cytoskeletal processes | SRF |
| PLXNB2 | Downregulated | Cytoskeletal processes | CREB1, SRF |
| EIF4G3 | Upregulated | RNA processing | – |
| NUDT12 | Upregulated | RNA processing | – |
| SART1 | Downregulated | RNA processing | CREB1, SRF |
| DDX31 | Downregulated | RNA processing | CREB1, SRF |
| DDX54 | Downregulated | RNA processing | SRF |
| MYBBP1A | Downregulated | RNA processing | SRF |
| NCALD | Upregulated | Vesicular activity | – |
| PREPL | Upregulated | Vesicular activity | CREB1 |
| TMED1 | Downregulated | Vesicular activity | SRF |
| ZFPL1 | Downregulated | Vesicular activity | CREB1, SRF |
| AGPAT3 | Downregulated | Metabolism | – |
| AACS | Downregulated | Metabolism | CREB1 |
| CTBS | Upregulated | Metabolism | – |
| DCAKD | Downregulated | Metabolism | CREB1 |
| HS2ST1 | Upregulated | Metabolism | – |
| ORMDL2 | Downregulated | Metabolism | – |
| PCK2 | Downregulated | Metabolism | – |
| PI4KB | Downregulated | Metabolism | – |
| UAP1L1 | Downregulated | Metabolism | CREB1 |
| COMT | Downregulated | Metabolism | CREB1 |