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Candidate genes identified in multi-omics analysis of patients with RTT and with a concordant alteration at the protein level in patients with RTT-like phenotypes
| Gene | Direction | Biological process | Potential TF |
|---|---|---|---|
| ARMC9 | Upregulated | Cytoskeletal processes | SRF |
| DDX31 | Downregulated | RNA processing | CREB1, SRF |
| DDX54 | Downregulated | RNA processing | SRF |
| MYBBP1A | Downregulated | RNA processing | SRF |
| COMT | Downregulated | Metabolism | CREB1 |
