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. 2023 Sep 15;3(9):1862–1874. doi: 10.1158/2767-9764.CRC-23-0087

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© 2023 The Authors; Published by the American Association for Cancer Research

This open access article is distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) license.

PMC Copyright notice

EphA2-NF is an independent diagnostic biomarker for pancreatic cancer from CA19-9. A and B, The ROC curves of serum EphA2-NF and CA19-9 to differentiate pancreatic cancer and HDs divided into high (A) and low (B) CA19-9 groups. The AUC for the diagnosis of pancreatic cancer by serum EphA2-NF (vs. test cohort HDs) for CA19-9 high or low was 0.87. C, There was no significant correlation between serum EphA2-NF and CA19-9 levels. D, Dot plot analysis of serum EphA2-NF in CA19-9–negative patients. E, ROC curves of serum EphA2-NF for pancreatic cancer with CA19-9 ≤2.0 U/mL.