TABLE 1.
Study population | No. of subjects | Prevalence (%) observed by the following:
|
rDNA LPS ELISAa
|
||||
---|---|---|---|---|---|---|---|
MIF assay | rDNA LPS ELISA | Sensitivity (%) | Specificity (%) | NPV (%) | PPV (%) | ||
Blood donors | 1,104 | 71.2 | 29.4 | 33.5 | 80.5 | 32.9 | 80.9 |
COPD patients | 271 | 72.0 | 53.1b | 64.1 | 75.0 | 44.9 | 86.8 |
The MIF assay was used as the gold standard.
P < 0.0001 compared to blood donors.