TABLE 4.

Published Clinical Trials Reporting Outcomes of Open Tibial Shaft Fractures

Studies	Total Sample	Open Tibia Sample	Number Centers	Duration (Years)	Enrolled/Center	Enrolled/Center/Year	Follow-Up Rate
FLOW trial [10]	2447	912	41	4	22	6	90%
SPRINT trial [11]	1226	392	29	5	13	3	93%
MOI IMN v. Ex-fix [12]	240	240	1	1.3	240	180	92.1%
TRUST trial [13]	501	114	43	4.5	3	<1	96%
LEAP study [14]	569	173	8	3	22	7	96%
INFINITI [15]	768	162	9	NR	18	NR	98%
Alberta cohort [16]	791	140	3	8	47	6	94%

The previous randomized trial conducted by the coordinating center and MOI is represented in bold.