Fig 2. CVB3 induces an expansion of activated CD8⁺ T cells in female Ifnar^-/- mice.

(A) Representative flow cytometry plots of CD62L expression on CD8⁺ T cells in uninfected and infected female Ifnar^-/- mice. The frequency (B) and number (C) of CD62L^lo CD8⁺ T cells in the spleen 5dpi in Ifnar^-/- mice. (D) Representative flow cytometry plots of CD11a and CD62L expression gated on CD8⁺ T cells in uninfected and infected female Ifnar^-/- mice. The frequency (E) and number (F) of CD11a^hiCD62L^lo CD8⁺ T cells in female mice 5dpi. All data are from two independent experiments with n = 7–8 mice per group and are shown as mean ± SEM. *p<0.05, **p<0.01, ***p<0.001, unpaired t-test.