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. 2023 Sep 5;19(9):e1011465. doi: 10.1371/journal.ppat.1011465

Fig 10. CD8+ T cells protect females from CVB3-induced lethality.

Fig 10

(A) Representative flow cytometry plots of T cells gated on CD4+ and CD8+ T cell expression in female Ifnar-/- mice treated with an anti-CD8α antibody or isotype control. (B) The frequency of CD8+ T cells in female Ifnar-/- mice treated with an anti-CD8α antibody or isotype control. ****p<0.0001, unpaired t-test. (C) Survival of CVB3-infected female mice treated with anti-CD8α or isotype control antibody. *p<0.05, Log-rank (Mantel-Cox) test, n = 10–11 mice per group.