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. 2023 Sep 15;18(9):e0291125. doi: 10.1371/journal.pone.0291125

Table 1. Protocol for evaluation of the hepatoprotective activity.

Group Number Group Status Treatment Specimen The volume of Treatment specimen (mg/kg) Group Abbreviation
1 Negative Control Physiological Saline 10mL/kg C
2 Disease control Carbon tetra chloride (CCl4) 3mL/kg CCl4
3 CCl4 + Silymarin Silymarin 3mL/kg+80mg/kg CCl4+S80
4 CCl4 + Silymarin Silymarin 3mL/kg+120mg/kg CCl4+S120
5 CCl4 + Silymarin Silymarin 3mL/kg+150mg/kg CCl4+S150
6 CCl4 + Gynura procumbens Gynura Procumbens 3mL/kg+500mg/kg CCl4+GP500
7 CCl4 + Gynura procumbens Gynura Procumbens 3mL/kg+750mg/kg CCl4+GP750
8 CCl4 + Gynura procumbens Gynura Procumbens 3mL/kg+1000mg/kg CCl4+GP1000
9 Silymarin Silymarin 80mg/kg S80
10 Silymarin Silymarin 120mg/kg S120
11 Silymarin Silymarin 150mg/kg S150
12 Gynura procumbens Gynura Procumbens 500mg/kg GP500
13 Gynura procumbens Gynura Procumbens 750mg/kg GP750
14 Gynura procumbens Gynura Procumbens 1000mg/kg GP1000