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. 2023 May 24;228(6):742–750. doi: 10.1093/infdis/jiad179

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© The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Odds ratios for osteoporosis according to the gSOS PRS, clinical risk factors, and TDF and bPI. Univariable and multivariable odds ratios and 95% CIs for osteoporosis according to (A) quintiles of the gSOS PRS, (B) quintiles of clinical risk factors, and (C) cumulative exposure to TDF and bPI. Results show simple logistic regression of associations with osteoporosis for 149 osteoporosis cases and 289 osteoporosis- and osteopenia-free controls. All odds ratios and 95% CIs are tabulated in Supplementary Table 2. bPI, boosted protease inhibitor; gSOS, genetically predicted heel quantitative ultrasound speed of sound; PRS, polygenic risk score; TDF, tenofovir disoproxil fumarate.