Table 3.
Antibacterial and antifungal activity of samples zone of inhibition in mm) and in percentage.
Compound details | Zone of inhibition in mm and percentage @ 25 μg/mL | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
S.A mm | S.A % | S.P mm | S.P % | E.C mm | E.C % | P.A mm | P. A % | C.A mm | C. A % | A.C mm | A.C % | |
Gram-positive bacteria | Gram-negative bacteria | Fungal strains | ||||||||||
2-phenyl benzoxazole scaffold | ||||||||||||
Sample -1 | 15 | 54% | 17 | 69% | 10 | 40% | 15 | 55% | 21 | 68% | 21 | 68% |
Sample -2 | 20 | 72% | 15 | 61% | 12 | 50% | 16 | 62% | 23 | 73% | 22 | 70% |
Sample -3 | 16 | 58% | 11 | 47% | 15 | 63% | 17 | 67% | 24 | 78% | 23 | 73% |
Sample -4 | 20 | 72% | 18 | 73% | 17 | 61% | 18 | 71% | 20 | 64% | 21 | 68% |
Sample -5 | 19 | 63% | 18 | 68% | 15 | 61% | 13 | 56% | 21 | 68% | 20 | 64% |
Sample -6 | 14 | 51% | 15 | 60% | 13 | 55% | 16 | 62% | 22 | 70% | 18 | 55% |
Sample -7 | 19 | 66% | 16 | 65% | 18 | 63% | 18 | 71% | 23 | 73% | 19 | 59% |
Sample -8 | 16 | 58% | 18 | 73% | 18 | 63% | 13 | 51% | 21 | 68% | 17 | 52% |
Sample -9 | 17 | 61% | 13 | 51% | 17 | 61% | 16 | 62% | 22 | 70% | 18 | 55% |
Sample -10 | 13 | 54% | 11 | 50% | 7 | 35% | 12 | 50% | 21 | 68% | 21 | 68% |
Sample -11 | 12 | 50% | 21 | 82% | 17 | 61% | 16 | 62% | 20 | 64% | 22 | 70% |
Sample -12 | 19 | 68% | 19 | 76% | 19 | 66% | 13 | 51% | 19 | 61% | 20 | 64% |
Sample -13 | 14 | 49% | 14 | 60% | 15 | 70% | 18 | 71% | 21 | 68% | 19 | 59% |
Sample -14 | 18 | 63% | 16 | 65% | 18 | 72% | 13 | 51% | 20 | 64% | 21 | 68% |
2-N-phenyl benzoxazole scaffold | ||||||||||||
Sample -15 | 17 | 61% | 18 | 73% | 16 | 60% | 16 | 62% | 21 | 68% | 23 | 73% |
Sample -16 | 15 | 53% | 17 | 67% | 19 | 76% | 14 | 50% | 22 | 70% | 22 | 70% |
Sample -17 | 19 | 66% | 16 | 65% | 16 | 65% | 17 | 67% | 20 | 64% | 21 | 68% |
Sample -18 | 21 | 81% | 19 | 82% | 20 | 85% | 22 | 76% | 19 | 61% | 20 | 64% |
Sample -19 | 20 | 72% | 12 | 47% | 19 | 77% | 14 | 60% | 21 | 68% | 19 | 59% |
Sample -20 | 18 | 63% | 15 | 61% | 17 | 69% | 15 | 59% | 23 | 73% | 17 | 52% |
Sample -21 | 23 | 80% | 22 | 85% | 22 | 90% | 20 | 72% | 22 | 70% | 19 | 59% |
Sample -22 | 21 | 78% | 19 | 76% | 20 | 80% | 17 | 67% | 21 | 68% | 21 | 68% |
Sample -23 | 16 | 58% | 20 | 79% | 16 | 66% | 12 | 47% | 20 | 64% | 20 | 64% |
Sample -24 | 14 | 50% | 17 | 69% | 17 | 69% | 18 | 71% | 19 | 61% | 21 | 68% |
Sample -25 | 19 | 66% | 16 | 65% | 18 | 73% | 13 | 51% | 22 | 70% | 18 | 55% |
Sample -26 | 21 | 78% | 17 | 69% | 19 | 78% | 12 | 47% | 21 | 68% | 22 | 70% |
Positive controls | ||||||||||||
Cefixime | 22 | 19 | 18 | 20 | ||||||||
29 | 26 | 25 | 28 | |||||||||
33 | 35 | 36 | 37 | |||||||||
Griseofulvin | 34 | 35 | ||||||||||
47 | 43 | |||||||||||
52 | 55 |
CA: Candida albicans; AC: Aspergillus Clavatus. SA: Staphylococcus aureus; SP: Streptococcus pyrogenes; EA: Escherichia coli; PA: Pseudomonas aeruinosa.