Table 3.

Advantages and disadvantages of C-ES and traditional ES

Advantages/disadvantages	C-ES	Traditional ES
Advantages	Can better achieve cell-to-cell interactions Good for cell infiltration and migration Efficient and rapid exchange of gases and substances Uniform distribution of the cells in the scaffold Use of nontoxic/low-toxicity solvent (better biocompatibility) The structure of the fibrous scaffold is fine Many cells can be processed	The process is simple and easy to operate Provides controllable micro/nanofiber structures Models the native ECM structure High surface area and porosity There is a wide variety of spinnable substances Spinning is cheap Products can be prepared with various properties
Disadvantages	The 3D structures are very difficult to implement The mechanical strength of the stent is low Difficult to balance maintenance of cellular activity with scaffold properties The cost is relatively high Selection of materials is relatively limited The parameter requirements are more stringent	The use of toxic solvents The distribution of the cells is not uniform Insufficient infiltration and migration of cells Insufficient structural refinement

ECM extracellular matrix, C-ES cell electrospinning, ES electrospinning