Table 1.
Qualitative analysis of included studies
| Authors | Year | Location | Study design | Embryos analysed (n) | Results (association with mosaicism) |
|---|---|---|---|---|---|
| Coll et al. | 2020 | Spain | Retrospective cohort study | 1708 | Positive association between mosaicism prevalence and paternal age |
| Dviri et al. | 2020 | Canada | Retrospective cohort study | 3118 | No significant association |
| Huang et al. | 2022 | China | Retrospective study | 1910 | Semen quality, fertilization method and detection system are independent factors associated with embryonic mosaicism |
| Kahraman et al. | 2020 | Turkey | Retrospective study | 1570 | When testicular sperm is used, the rate of mosaicism increases |
| Martin et al. | 2021 | Spain | Retrospective cohort study | 1511 | No significant association |
| Nakhuda et al. | 2018 | Canada | Retrospective cross-sectional study | 1743 | |
| Rodrigo et al. | 2020 | Spain | Retrospective observational study | 111,860 | Older female and male patients showed higher rates of high-mosaic degree. Severe oligozoospermic patients had higher rates of mosaicism |