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. 2023 Sep 15;14:174. doi: 10.1007/s12672-023-00784-2

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Heterogeneity of NK/T cells in lung adenocarcinoma and brain metastases. A UMAP plot shows eleven subclusters of the NK/T cells. B UMAP plot of NK/T cells revealing nine subtypes. C Canonical cell markers used to identify NK/T cell subtypes. D The UMAP plot showing CD8 + T cells origin. E The UMAP plot showing NK cells origin. F–H Violin plot indicating the naive (left), cytotoxic (middle), and exhausted (right) scores of CD8 + T cells from lung adenocarcinoma and brain metastases. I–K Violin plot indicating the naive (left), cytotoxic (middle), and exhausted (right) scores of NK cells from lung adenocarcinoma and brain metastases