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. 2023 Sep 15;14:174. doi: 10.1007/s12672-023-00784-2

Fig. 5.

Fig. 5

Heterogeneity of endothelial cells in lung adenocarcinoma and brain metastases. A UMAP plot shows five subclusters of the endothelial cells. B UMAP plot of endothelial cells revealing two subtypes. C Canonical cell markers used to identify endothelial cells subtypes. D The UMAP plot showing endothelial cells origin. E Violin plots of the expression of several marker genes, including COL4A1, COL4A2, HSPG2, COL15A1, and SPARC, in endothelial cells from lung adenocarcinoma and brain metastases. F Differences in pathway activities scored per cell by GSVA between lung adenocarcinoma and brain metastases endothelial cells