Table 2. ADMET and SwissADME properties of oxazole compounds (1-6).

Compound	log Kp (cm/s)	GI absorption	BBB permeant	Pgp substrate	CYP1A2 inhibitor	CYP2C19 inhibitor	CYP2C9 inhibitor	CYP2D6 inhibitor	CYP3A4 inhibitor
1	-6	High	Yes	No	Yes	Yes	Yes	Yes	Yes
2	-5.58	High	Yes	Yes	Yes	Yes	Yes	Yes	Yes
3	-5.65	High	Yes	Yes	Yes	Yes	Yes	Yes	Yes
4	-5.98	High	No	Yes	No	Yes	Yes	Yes	Yes
5	-5.12	High	No	Yes	No	Yes	Yes	Yes	Yes
6	-6.28	High	No	Yes	No	Yes	Yes	Yes	Yes
Azithromycin	-8.01	Low	No	Yes	No	No	No	No	No
Sulfanilamide	-7.79	High	No	No	No	No	No	No	No
Sulfamethoxazole	-7.21	High	No	No	No	No	No	No	No