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. 2023 Jan 31;19(1):111–116. doi: 10.6026/97320630019111

Table 4. Toxicity profile of selected oxadiazole compounds (1-6).

			Toxicity
Compound	^aLD₅₀ (mg/kg)	Class	HEPATOTOXICITY	CARCINOGENICITY	IMMUNOTOXICITY	MUTAGENICITY	CYTOTOXICITY
1	1190mg/kg	4	Active	Inactive	Active	Inactive	Inactive
2	300mg/kg	3	Active	Active	Inactive	Inactive	Inactive
3	1000mg/kg	4	Active	Active	Inactive	Inactive	Inactive
4	1000mg/kg	4	Active	Active	Inactive	Inactive	Inactive
5	300mg/kg	3	Active	Active	Inactive	Inactive	Inactive
6	1350mg/kg	4	Active	Active	Inactive	Active	Inactive
Doxorubicin	205mg/kg	3	Inactive	Inactive	Active	Active	Active
Paclitaxel	134mg/kg	3	Inactive	Inactive	Active	Inactive	Active
Tamoxifen	1190mg/kg	4	Active	Inactive	Active	Inactive	Inactive