Table 3. Lipinski and Veber rules of selected oxazole compounds (1-5).

Compound	MW	iLogP	HBD (nOHNH)	HBA (nON)	nrotb	MR	TPSA	Lipinski #violations	Bio availability score
Lipinski*	≤500	≤5	≤5	≤10	≤10	-	-
Veber**	-	-	-	-	-	-	≤ 140
1	422.43	4.17	0	6	6	122.66	77.83	0	0.55
2	422.43	4.21	0	6	6	122.66	77.83	0	0.55
3	350.76	3.26	0	5	3	96.69	68.6	0	0.55
4	358.39	3.61	0	5	4	106.26	68.6	0	0.55
5	362.34	3.02	1	7	4	100.19	98.06	0	0.55
Amoxicillin	365.4	1.46	4	6	5	94.59	158.26	0	0.55
Moxifloxacin	401.43	2.78	2	6	4	114.05	83.8	0	0.55
Sulfanilamide	172.2	0.61	2	3	1	41.84	94.56	0	0.55
Sulfamethoxazole	253.28	1.03	2	4	3	62.99	106.6	0	0.55