Table 3.
Comparison of Carba-R and conventional drug susceptibility testing (DST)
| Organism | DST | CR gene +ve | CR gene –ve | |||
|---|---|---|---|---|---|---|
| CR | CS | CR | CS | CR | CS | |
| Klebsiella pneumoniae (n = 77) | 48 (62.33%) | 29 (37.66%) | 43 (89.58%) | 1 (3.4%) | 5 (10.41%) | 28 (96.5%) |
| Escherichia coli (n = 39) | 4 (10.25%) | 35 (89.74%) | 4 (100%) | 3 (8.57%) | 0 | 32 (91.42%) |
| Enterobacter cloacae (n = 6) | 2 (33.33%) | 4 (66.66%) | 2 (100%) | 0 | 0 | 4 (100%) |
| Citrobacter koseri (n = 2) | 0 | 2 | – | – | 0 | 2 |
| Serratia marcescens (n = 2) | 0 | 2 | – | – | 0 | 2 |
| Morganella morganii (n = 1) | 0 | 1 | – | 1 | – | – |
| Acinetobacter baumannii (n = 16) | 11 (68.75%) | 5 (31.25%) | 1 (9.09%) | 0 | 10 (90.9%) | 5 (100%) |
| Pseudomonas aeruginosa (n = 7) | 4 (57.14%) | 3 (42.85%) | 2 (50%) | 0 | 2 (50%) | 3 (100%) |
| Pseudomonas stutzeri (n = 1) | 0 | 1 | – | – | 0 | 1 |
| Pseudomonas putida (n = 2) | 0 | 2 | – | – | 0 | 2 |
| Burkholderia pseudomallei (n = 2) | 0 | 2 | – | – | 0 | 2 |
| Burkholderia cepacia (n = 2) | 2 | – | – | 2 | 0 | |
| Aeromonas hydrophila (n = 3) | 2 | 1 | 1 | 0 | 1 | 1 |
| Ralstonia mannitolilytica (n = 1) | 0 | 1 | – | – | 0 | 1 |
| Stenotrophomonas maltophilia (n = 2) | – | – | – | – | – | – |
| Elizabethkingia meningoseptica (n = 1) | – | – | – | – | – | – |
*Note: Four patients who had a negative Carba-R report, had polymicrobial bacteremia from the same blood culture bottle each with two bacteria and were considered as separate isolates