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Validation of GPCR score using single-cell transcriptome analysis. A, B t-SNE plots displaying 11 clusters A and 9 samples B of melanoma. C t-SNE plot annotating seven cell types (T cells, melanoma, fibroblasts, macrophages, endothelial cells, B cells, and plasma cells) using classical marker genes. D Heatmap of marker genes used for cell type annotation. E, F Visualization of GPCR score at single-cell level using feature plot E and violin plot (F). GPCR G protein-coupled receptor
