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. 2023 Sep 16;17(1):116. doi: 10.1186/s13065-023-01003-3

Table 2.

Cell viability % of MCF-10 A cells upon treatment with 50 µM of compounds 7a-x for 96 h and IC50 of compounds 7a-x & Doxorubicin in A-549, MCF-7, Panc-1 and HT-29 after 48 h incubation

Compound Cell viability % in MCF-10 A
(50 µM)
IC50 ± SEM (µM)
A-549 MCF-7 Panc-1 HT-29
7a 91 9.90 ± 1.10 9.20 ± 1.10 10.40 ± 1.30 11.15 ± 1.40
7b 88 8.20 ± 0.90 7.90 ± 0.80 8.40 ± 1.00 9.10 ± 1.10
7c 87 4.70 ± 0.50 4.15 ± 0.50 5.20 ± 0.40 5.50 ± 0.50
7d 89 9.70 ± 1.10 8.90 ± 1.10 10.30 ± 1.30 11.10 ± 1.40
7e 87 1.60 ± 0.30 1.25 ± 0.08 1.70 ± 0.30 1.95 ± 0.30
7f 87 2.15 ± 0.50 2.05 ± 0.50 2.40 ± 0.60 2.70 ± 0.50
7g 91 1.80 ± 0.60 1.45 ± 0.30 1.90 ± 0.50 2.10 ± 0.60
 h 87 1.95 ± 0.60 1.75 ± 0.40 2.05 ± 0.50 2.25 ± 0.60
7i 84 9.70 ± 1.10 9.20 ± 1.00 10.15 ± 1.20 10.20 ± 1.30
7j 89 9.95 ± 1.10 9.40 ± 1.20 10.30 ± 1.20 10.70 ± 1.10
7k 91 1.20 ± 0.20 0.95 ± 0.08 1.30 ± 0.20 1.40 ± 0.20
7l 89 1.45 ± 0.30 1.10 ± 0.10 1.50 ± 0.30 1.65 ± 0.30
7m 94 1.40 ± 0.50 1.20 ± 0.08 1.50 ± 0.20 1.85 ± 0.40
7n 92 1.90 ± 0.60 1.65 ± 0.30 2.05 ± 0.50 2.20 ± 0.60
7o 89 7.60 ± 0.30 7.10 ± 0.60 8.20 ± 1.20 8.60 ± 0.40
7p 87 2.50 ± 0.50 2.10 ± 0.20 3.10 ± 0.40 3.30 ± 0.40
7q 94 3.40 ± 0.40 3.02 ± 0.30 3.80 ± 0.50 3.70 ± 0.50
7r 91 3.60 ± 0.50 3.10 ± 0.50 3.90 ± 0.50 4.20 ± 0.50
7s 87 3.80 ± 0.60 3.15 ± 0.50 4.30 ± 0.60 4.55 ± 0.60
7t 88 10.60 ± 1.10 10.10 ± 1.00 10.90 ± 1.20 10.80 ± 1.20
7u 90 2.25 ± 0.50 2.10 ± 0.08 2.40 ± 0.20 2.70 ± 0.50
7v 87 2.45 ± 0.50 2.20 ± 0.08 2.60 ± 0.20 2.90 ± 0.50
7w 91 10.90 ± 1.10 10.20 ± 1.20 11.15 ± 1.20 11.20 ± 1.30
7x 85 11.50 ± 1.20 10.800 ± 1.10 11.80 ± 1.20 12.50 ± 1.50
Doxorubicin - 1.21 ± 0.10 0.90 ± 0.10 1.41 ± 0.10 1.01 ± 0.10