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. 2023 Sep 16;17(1):116. doi: 10.1186/s13065-023-01003-3

Table 3.

Inhibitory activities of selected compounds against EGFR and BRAFV600E

Compound EGFR Inhibition
IC50 ± SEM (µM)
BRAF V600E Inhibition
IC50 ± SEM (µM)
7e 1.15 ± 0.20 0.90 ± 0.10
7g 1.70 ± 0.20 1.00 ± 0.20
7h 2.30 ± 0.20 2.70 ± 0.30
7k 0.55 ± 0.10 1.70 ± 0.20
7L 0.80 ± 0.10 1.90 ± 0.20
7m 0.90 ± 0.10 2.20 ± 0.20
7n 1.40 ± 0.20 3.70 ± 0.20
7p 3.50 ± 0.30 4.20 ± 0.30
7q 3.90 ± 0.30 4.70 ± 0.30
7v 2.80 ± 0.30 3.10 ± 0.20
Erlotinib 0.08 ± 0.01 0.06 ± 0.01