Table 8.

ADMET Results of the test with SwissADME for the target compounds 7k, 7l, 7m, and Erlotinib

Compound	M.Wt	Fraction Csp3	RB	HBA	HBD	MR	TPSA	Log P	GI absorption	BBB perm.	Lip. V.	Bio. Sc.
7k	587.65	0.06	11	7	2	166.67	148.30	3.28	Low	No	Yes	0.55
7l	622.09	0.06	11	7	2	171.68	148.30	5.87	Low	No	No	0.17
7m	617.67	0.09	12	8	2	173.17	157.53	5.41	Low	No	Yes	0.55
Erlotinib	393.44	0.27	10	6	1	111.40	74.73	3.28	High	Yes	Yes	0.55