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. 2023 Sep 15;19:17448069231193368. doi: 10.1177/17448069231193368

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© The Author(s) 2023

This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 2. — (a). Log10 10000X 50% PWT over time. Animals developed significant STZ-induced mechanical hypersensitivity from baseline to pre-SCS. Con-, HF- and DTM-SCS but not Sham-SCS significantly reduced hypersensitivity after 48 hours of continuous stimulation. (b). Log10 10000X 50% PWT as percentage of pre-SCS. Con-, HF- and DTM-SCS significantly increased Log10 10000X 50% PWT values as compared to sham after 48 hours of stimulation. Con, HF and DTM SCS do not significantly differ from each other. *, ∼,+,#p < 0,05; **, ∼∼,++,##p < 0,01; ***,∼∼∼,+++,###p < 0,001.