Table 2.
Results of Cox Proportional Risk Regression Model Analysis of the Relationship Between Different Obesity Indices and the Development of DKD
| HR (95% CI) | |||
|---|---|---|---|
| Model 1 | Model 2 | Model 3 | |
| BRI | |||
| Q1 (<3.47) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
| Q2 (3.47–4.17) | 1.057(0.877,1.273)* | 1.072(0.889,1.294)* | 1.061(0.879,1.281)* |
| Q3 (4.17–5.06) | 1.348(1.127,1.612) | 1.247(1.039,1.495) | 1.229(1.024,1.475) |
| Q4 (>5.06) | 1.555(1.305,1.853) | 1.411(1.178,1.689) | 1.356(1.131,1.626) |
| P for trend | <0.001 | 0.001 | 0.004 |
| LAP | |||
| Q1 (<17.67) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
| Q2 (17.67–29.62) | 1.160(0.968,1.390)* | 1.183(0.986,1.419)* | 1.158(0.964,1.391) |
| Q3 (29.62–48.94) | 1.354(1.134,1.616) | 1.337(1.116,1.601) | 1.241(1.032,1.494) |
| Q4 (>48.94) | 1.367(1.145,1.631) | 1.354(1.128,1.625) | 1.268(1.058,1.521) |
| P for trend | 0.001 | 0.004 | 0.030 |
| VAI | |||
| Q1 (<0.91) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
| Q2 (0.91–1.45) | 1.111(0.929,1.328)* | 1.127(0.941,1.349)* | 1.075(0.896,1.288)* |
| Q3 (1.45–2.31) | 1.267(1.078,1.391) | 1.223(1.042,1.406) | 1.121(1.036,1.343) |
| Q4 (>2.31) | 1.325(1.155,1.494) | 1.317(1.141,1.493) | 1.265(1.101.1.398) |
| P for trend | <0.001 | <0.001 | 0.008 |
| WC | |||
| Q1 (<81.50) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
| Q2 (81.50–87.0) | 1.191(0.997,1.424)* | 1.162(0.970,1.393)* | 1.130(0.942,1.355)* |
| Q3 (87.0–94.0) | 1.311(1.096,1.569) | 1.280(1.064,1.540) | 1.245(1.033,1.499) |
| Q4 (>94.0) | 1.546(1.290,1.852) | 1.461(1.211,1.763) | 1.379(1.141,1.688) |
| P for trend | <0.001 | 0.001 | 0.007 |
| BMI | |||
| Q1 (<23.33) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
| Q2 (23.33–25.60) | 1.020(0.851,1.222)* | 1.055(0.880,1.265) | 1.041(0.868,1.249)* |
| Q3 (25.60–28.19) | 1.225(1.029,1.459) | 1.262(1.059,1.506) | 1.221(1.022,1.459) |
| Q4 (>28.19) | 1.299(1.092,1.544) | 1.354(1.135,1.616) | 1.301(1.088,1.556) |
| P for trend | <0.001 | 0.002 | 0.010 |
Notes: Patients were grouped by quartile. Model 1: adjusted for no variable. Model 2: adjusted for age, sex, smoking, drinking, duration of diabetes, medication situation. Model 3: adjusted for model 2 plus HbA1c, SBP, DBP, Scr. *P>0.05.
Abbreviations: BMI, body mass index; WC, waist circumference; VAI, visceral adiposity index; LAP, lipid accumulation product; BRI, body roundness index.