Table 3.

Final probe ratio from MLPA of representative samples carrying CYP450 copy number alterations

Samples	CYP1B1		CYP2A6				CYP2C9					CYP2E1
	Exon 2	Exon 3	Exon 1	Exon 2	Exon 3	Exon 5	Exon 1	Exon 7	Exon 8-1	Exon 8-2	Exon 9	Exon 5	Exon 6	Exon 8
FVN48	0.89	0.87	0.41	0.42	0.5	0.43	1.1	1.18	1.16	1.06	0.92	0.95	0.93	0.88
FVN74	0.89	0.85	0	0	0	0	1	1	1	0.96	0.99	1.02	0.94	1.11
MVN23	1.34	1.53	1.15	1.14	1.16	1.15	0.47	0.55	0.61	0.56	0.58	1.09	1.08	0.99
FVN73	1.08	0.99	1.05	1.07	1.04	1.08	1	0.99	0.98	0.92	0.96	0.51	0.51	0.47
FVN46	1.04	1.1	0.94	0.92	1.17	1.2	1.17	1.03	1.1	0.82	0.93	1.37	1.38	1.63
FVN98	0.86	0.86	0.97	0.98	1.16	0.91	1.06	0.96	1.02	1.28	1.11	1.36	1.37	1.37

Final probes ratio indicated deletions (underline); final probes ratio indicated duplications (bold).

MLPA, multiplex ligation-dependent probe amplification.